Efficacy of Platelet-Rich Plasma Injections for Knee Osteoarthritis

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Knee osteoarthritis in the adult population is one of the leading causes of disability in the United States. Approximately 50% of patients between 65- and 70-years old experience some degree of osteoarthritis in their knee(s). Prolonged weight bearing and ambulatory experiences throughout life predispose a patient to destruction of the cartilaginous surfaces within the tibiofemoral joint, resulting in pain and gait abnormalities which are often negatively affecting activities of daily living. Many treatment options have been implemented in past years to assist a patient with pain relief and gait ambulation. However, platelet-rich plasma (PRP) injections are theorized to promote cartilage regeneration and mediate inflammatory factors associated with osteoarthritis. This review addresses literature on platelet-rich plasma (PRP) injections for knee osteoarthritis, focusing on potential uses, benefits, and comparisons with other knee osteoarthritis treatment options.

First Advisor

William Schweinle

Research Area

Physician Assistant Studies

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