Sanford School of Medicine Affiliation

Transplantation and Surgery

Document Type

Article

Disciplines

Medicine and Health Sciences | Surgery

Publication Date

1-1-2010

Keywords

Adult, Cholangitis, Diagnosis, Differential, Diagnostic Imaging, Eosinophilia, Humans, Male

Abstract

BACKGROUND: Eosinophilic cholangitis (EC) is a rare benign disorder of the biliary tract which can cause biliary obstruction. Similar to other disease processes involving the bile ducts, this disorder can pose a difficult diagnostic challenge as it can mimic cholangiocarcinoma.

METHODS: A systematic search of the scientific literature was carried out using PubMed to access all publications related to EC. Search keywords that were utilized included "eosinophilic cholangitis," "etiology," "treatment," and "obstructive jaundice." Results. Twenty-three cases of EC have been reported. Nineteen patients (82.6%) who presented with EC remain disease-free; 15 of these 19 patients (78.9%) with followup time remain disease-free at a mean of 9.7 months (range, 2-24 months).

CONCLUSION: EC is a rare form of biliary obstruction which can masquerade as a malignancy. Unlike cholangiocarcinoma, EC occurs more commonly in younger patients and in men. Most patients will require surgical treatment.

Journal Title

HPB Surgery : A World Journal of Hepatic, Pancreatic and Biliary Surgery

Volume

2010

First Page

906496

Last Page

906496

PubMed ID

21076681

ISSN

1607-8462

MeSH Headings (Medical Subject Headings)

Adult; Cholangitis; Diagnosis, Differential; Diagnostic Imaging; Eosinophilia; Humans; Male

DOI

10.1155/2010/906496

Creative Commons License

Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.

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