Date of Award

Spring 5-9-2026

Document Type

Honors Thesis

Department/Major

Basic Biomedical Science

First Advisor

Lee Baugh

Second Advisor

Taylor Bosch

Third Advisor

Anna Simonson

Keywords

anterior supramarginal gyrus, motor learning, chopsticks

Subject Categories

Medicine and Health Sciences

Abstract

The left anterior supramarginal gyrus (aSMG) is recognized as a fundamental cortical region involved in the mastery of skilled tool-use. Although various research studies have revealed that anodal transcranial Direct Current Stimulation (atDCS) over the cortex has the potential to boost manual dexterity, the impact of stimulating the aSMG is less understood in relation to the learning process. Within this study, there was a chopstick-based marble task to discover if atDCS applied to the left aSMG was capable of facilitating the acquisition of a novel motor skill. Concurrent electroencephalography (EEG) was used to measure the changes in neural synchrony within the beta and gamma frequency bands during a critical period of action observation. The findings have indicated that rather than increasing overall connectivity, the atDCS modified the functional association between the different brain states and physical performance. More specifically, there was a significant interaction where interhemispheric beta-band connectivity (C3-C4) became a robust predictor of task success within the simulation group during the latter half of the observation window. These results indicate aSMG stimulation primes the motor system through making specific neural coordination patterns more behaviorally relevant. This study has clarified the aSMG’s role within skill acquisition as well as suggested new avenues relating to the targeted neurostimulation in rehabilitation settings for those with impaired motor control.

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